MSE Seminar - Professor Eugenia Kharlampieva, Univ. of Alabama - Birmingham
Dr. Eugenia Kharlampieva, Chemistry Department, University of Alabama-Birmingham,
“Nanoengineered Materials for Drug Delivery and Cell Transplatation”
Bio-inspired fabrication of biologically-active and stimuli-sensitive nanostructured materials are of increasing interest in bio- and nanotechnology. This talk will focus on functional nanothin coatings and hollow microparticles (capsules) obtained by assembly of synthetic and biological macromolecules on inorganic templates and living cells. We will discuss pH-triggered volume and shape transitions in these materials to be used for controlled drug delivery. We will also address the application of nanostructured coatings in cell-based transplantation therapy. We will present immunomodulatory coatings with diminished inflammatory immune responses deposited on surfaces of mammalian pancreatic islet cells. These materials provide prolonged cell viability and function to be used in diabetes treatment.
Eugenia Kharlampieva is an Associate Professor of Polymer Chemistry at the Department of Chemistry at the University of Alabama at Birmingham (UAB). She received her Ph.D. in Polymer Science from the Stevens Institute of Technology and postdoctoral training in Materials Science and Engineering at the Georgia Institute of Technology. Her research centers at the intersection of polymer chemistry, nanotechnology, and biomedical science to develop new materials for therapeutic applications. She has authored more than 70 peer-reviewed publications, four book chapters, and six patents.
Dr. Kharlampieva received the NSF CAREER Award in Polymers, the UAB College of Arts and Sciences Interdisciplinary Innovation Award, and was named as an Emerging Investigator by the Royal Society of Chemistry, Journal of Materials Chemistry B, in 2014. Dr. Kharlampieva is an Executive Committee member at Oak Ridge National Lab (ORNL), SHUG (SNS and HFIR User Group). She also serves on an Advisory Committee Board in Neutron Scattering at Oak Ridge National lab (ORNL), UT/ORNL DOE EPSCoR and at the Editorial Board of Journal of Analytical & Bioanalytical Techniques.