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Valeria Tohver Milam
Assistant Professor

Georgia Institute of Technology
Materials Science and Engineering
771 Ferst Drive, N.W.
Atlanta, GA 30332-0245

Office: Molecular Sciences and Engineering Bldg., Room 3100J
Phone: 404.894.2845  | Fax: 404.894.9140
valeria.milam@mse.gatech.edu

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B.S. Materials Science & Engineering, University of Florida (1993)
M.S. Materials Science & Engineering, University of Illinois, Urbana-Champaign (1997)
Ph.D. Materials Science & Engineering, University of Illinois, Urbana-Champaign (2001)

Valeria Tohver Milam joined the School of Materials Science and Engineering at Georgia Institute of Technology as an assistant professor in July 2004.  She received her B.S. in Materials Science and Engineering with Honors from the University of Florida in 1993.   After completing her M.S. degree (1997) in MSE at the University of Illinois, Urbana-Champaign, she interned at Sandia National Laboratories.  She then completed her doctoral work at UIUC studying the phase behavior, structure and properties of nanoparticle-microsphere suspensions. Experimental results suggested a novel colloidal stabilization mechanism known as nanoparticle “haloing” in which otherwise negligibly charged microspheres become effectively charge-stabilized by their surrounding shell of highly charged nanoparticles. 

After finishing her Ph.D. in 2001, her postdoctoral studies at the University of Pennsylvania focused on DNA-mediated colloidal assembly.  The degree of specific attraction between DNA-grafted microspheres was found to vary with sequence length, sequence concentration and ionic strength.  A variety of structures such as colloidal chains, rings and micelles were formed by varying the particle size ratio and suspension composition.

Research Interests

  • Using specific recognition between biological macromolecules (e.g. proteins, DNA, etc.) to induce assembly of colloidal materials

Dr. Milam’s current research interests focus on designing and characterizing colloids functionalized with biologically-relevant macromolecules such as oligonucleotides and cellular adhesion molecules.  The specific recognition between matching macromolecules such as complementary DNA strand pairs allows for programmable adhesion between either complementary particle surfaces or between complementary particle and matrix interfaces. Using a variety of biocompatible and biodegradable materials as the colloidal substrate, these biocolloids will serve as building blocks to fabricate novel material constructs ranging from stimuli-responsive hybrid materials to therapeutic delivery vehicles.

Recent Awards

  • Georgia Cancer Coalition Distinguished Cancer Scholar
  • Lockheed Martin Aeronautics Company Dean's Award for Teaching Excellence (2005)

Selected Publications

  1. C.K. Tison, V.T. Milam, “Reversing DNA-mediated adhesion at a fixed temperature,” Langmuir 2007 23 (19) 9728-9736
  2. P.L. Biancaniello, J.C. Crocker, D.A. Hammer, V.T. Milam, “DNA-mediated phase behavior of microsphere suspensions,” Langmuir 2007 23 (5) 2688-2693.
  3. V.T. Milam, A.L. Hiddessen, J.C. Crocker, D.J. Graves, D.A. Hammer, “DNA-driven assembly of bidisperse, micron-sized colloids” Langmuir 2003 19 (24) 10317-10323.
  4. V. Tohver, J.E. Smay, A. Braem, P.V. Braun, J.A. Lewis, “Nanoparticle halos: A new colloidal stabilization mechanism,” Proc. Natl. Acad. Sci. USA, 2001 98 (16) 8950-8954.

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